Pesticides >> Insecticides >> Cartap
Cartap
Cartap98%TC
Cartap 50%SP
Insecticide
2-dimethylaminopropane-1,3-dithiol
Cartap NOMENCLATURE
Common name cartap (BSI, E-ISO, (m) F-ISO, JMAF)
IUPAC name S,S'-(2-dimethylaminotrimethylene) bis(thiocarbamate)
Chemical Abstracts name S,S'-[2-(dimethylamino)-1,3-propanediyl]
dicarbamothioate
CAS RN [15263-53-3] Development codes TI-1258 (Takeda)
cartap hydrochloride
Common name cartap hydrochloride
CAS RN [15263-52-2] cartap monohydrochloride; [22042-59-7] cartap,
unspecified hydrochloride EEC no. 239-309-2
Cartap PHYSICAL CHEMISTRY
Mol. wt. 237.3 M.f. C7H15N3O2S2
Cartap COMMERCIALISATION
History Insecticide reported by M. Sakai et al. (Jpn. J. Appl. Entomol.
Zool., 1967, 11, 125), its action and structure-activity relationships
reviewed (K. Konishi, Pestic. Chem. [Congr. Pestic. Chem., 2nd,
1971], 1972, 1, 179; M. Sakai & Y. Sato, ibid., p. 445; M. Sakai,
Jpn. Pestic. Inf., 1971, No. 6, p. 15; 1978, No. 34, p. 22). The
hydrochloride introduced by Takeda Chemical Industries, Ltd and
first marketed in Japan in 1967. Patents GB 1126204; US 3332943;
FR 1452338 Manufacturers Hunan Linxiang; Kuo Ching; Takeda
Cartap APPLICATIONS
Biochemistry Analogue or propesticide of the natural toxin nereistoxin.
Nicotinergic acetylcholine blocker, causing paralysis by blocking
cholinergic transmissions in the central nervous systems of insects.
Mode of action Systemic insecticide with stomach and contact action.
Insects discontinue feeding, and die of starvation.
cartap hydrochloride
Uses Cartap hydrochloride is used, at c. 0.4-1.0 kg/ha, for control
of chewing and sucking insects (particularly Lepidoptera and Coleoptera),
at almost all stages of development, on many crops, including rice
(Chilo suppressalis, Cnaphalocrocis medinalis, Lissorhoptrus oryzophilus
and rice-leaf beetle), potatoes, cabbage and other vegetables (Agromyzidae,
Leptinotarsa decemlineata and Plutella xylostella); also on soya
beans, peanuts, sunflowers, maize, sugar beet, wheat, pearl barley,
pome fruit, stone fruit, citrus fruit, vines, chestnuts, ginger,
tea, cotton, and sugar cane. Phytotoxicity May be phytotoxic to
cotton, tobacco, and apples, under certain soil and climatic conditions.
Formulation types DP; GR; SP. Compatibility Not compatible with
pesticides which are alkaline. Selected tradenames: 'Padan' (Takeda);
'Sanvex' (Takeda, Nagarjuna Agrichem)
Cartap OTHER TRADENAMES
'Caldan' (Takeda, Dhanuka); 'Pilartap' (Pilarquim); 'Vicarp' (Vipesco)
mixtures: 'Vipami' (+ isoprocarb) (Vipesco)
cartap hydrochloride
'Cadan' (Takeda); 'Patap' (Takeda); 'Thiobel' (Takeda); 'Vegetox'
(Takeda); 'Kritap' (Krishi Rasayan)
ANALYSIS
Product analysis by colorimetry (CIPAC Handbook, 1988, D, 24). Residue
analysis by glc or by polarography (K. Nishi et al., Anal. Methods
Pestic. Plant Growth Regul., 1973, 7, 371).
MAMMALIAN TOXICOLOGY
Reviews FAO/WHO 74 (see part 2 of the Bibliography).
ADI (JMPR) ADI withdrawn [1995].
hydrochloride
Oral Acute oral LD50 for male rats 345, female rats 325, male mice
150, female mice 154 mg/kg. Skin and eye Acute percutaneous LD50
for mice >1000 mg/kg; no irritation to skin or eyes in rabbits.
Inhalation LC50 (6 h) for rats >0.54 mg/l. NOEL (2 y) for rats
10 mg/kg b.w. daily; (1.5 y) for mice 20 mg/kg b.w. daily. Toxicity
class WHO (a.i.) II; EPA (formulation) II EC hazard Xn; R21/22
Cartap ECOTOXICOLOGY
cartap hydrochloride
Fish LC50 for carp 1.6 mg/l (24 h) and 1.0 mg/l (48 h). Other aquatic
spp. LC50 (24 h) for Moina macrocopa 12.5-25 mg/l. Bees Moderately
toxic to honeybees.