Products >> Fungicides >> Carbendazim
Carbendazim
Carbendazim 50%SC
Carbendazim 75% WDG
Fungicide
FRAC 1; benzimidazole
Carbendazim NOMENCLATURE
Common name carbendazim (BSI, E-ISO); carbendazime ((f) F-ISO);
carbendazol (JMAF)
IUPAC name methyl benzimidazol-2-ylcarbamate
Chemical Abstracts name methyl 1H-benzimidazol-2-ylcarbamate
Other names MBC; BMC CAS RN [10605-21-7] EEC no. 234-232-0 Development
codes BAS 346F (BASF); Hoe 017411 (Hoechst); DPX-E 965 (Du Pont)
Carbendazim APPLICATIONS
Biochemistry Reported to inhibit beta-tubulin synthesis. Mode of
action Systemic fungicide with protective and curative action. Absorbed
through the roots and green tissues, with translocation acropetally.
Acts by inhibiting development of the germ tubes, the formation
of appressoria, and the growth of mycelia. Uses Control of Septoria,
Fusarium, Erysiphe and Pseudocercosporella in cereals; Sclerotinia,
Alternaria and Cylindrosporium in oilseed rape; Cercospora and Erysiphe
in sugar beet; Uncinula and Botrytis in grapes; Cladosporium and
Botrytis in tomatoes; Venturia and Podosphaera in pome fruit and
Monilia and Sclerotinia in stone fruit. Application rates vary from
120-600 g/ha, depending on crop. A seed treatment (0.6-0.8 g/kg)
will control Tilletia, Ustilago, Fusarium and Septoria in cereals,
and Rhizoctonia in cotton. Also shows activity against storage diseases
of fruit as a dip (0.3-0.5 g/l). Formulation types OP; SC; SL; WG;
WP; Seed treatment. Compatibility Incompatible with alkaline materials.
Selected tradenames: 'Bavistin' (BASF); 'Derosal' (Aventis); 'Addstem'
(Headland); 'Aimcozim' (Aimco); 'Arrest' (RPG); 'Bencarb' (Reposo);
'Carbate' (PBI); 'Carezim' (Efthymiadis); 'Cekudazim' (Cequisa);
'Dhanustin' (Dhanuka); 'Fungy' (Ramcides); 'Hinge' (Quadrangle);
'Kolfugo Super' (Agro-Chemie); 'Occidor' (Agriphar); 'Sabendazim'
(Sanonda); 'Volzim' (Ralchem); 'Zen' (Nagarjuna Agrichem); mixtures:
'Sportak Alpha' (+ prochloraz) (Aventis); 'Troika' (+ fenbuconazole)
(Aventis); 'Vista C' (+ fluquinconazole) (Aventis)
Carbendazim OTHER TRADENAMES
'Agni' (Parry); 'Bendazim' (AgroSan, Agrochem); 'Benfil' (Indofil);
'C-Flo' (Stefes); 'Chemcarb' (Chemiplant); 'Headland Addstem' (Headland);
'Headland Regain' (Headland); 'Mooncoin' (GreenCrop); 'MSS Mircarb'
(Mirfield); 'Pacarzim' (Papaeconomou); 'Pilarstin' (Pilarquim);
'Spotfree' (Crop Health); 'Stefes C-Flo 2' (Stefes); 'Stefes Derosal+A937'
(Stefes); 'Tartan' (Chemiplant); 'Tripart Defensor' (Tripart); 'Twincarb'
(Vitax); 'Vicarben' (Vipesco) mixtures: 'Calidan' (+ iprodione)
(Aventis); 'Contrast' (+ flusilazole) (Du Pont); 'Duett' (+ epoxiconazole)
(BASF); 'Inca' (+ tebuconazole) (spray, Belgium) (Bayer, BASF);
'Konker' (+ vinclozolin) (BASF); 'Novak' (+ prochloraz) (Aventis);
'Alto Ambel' (+ cyproconazole) (Syngenta, Bayer); 'Alto Combi' (+
cyproconazole) (Syngenta, Bayer); 'Apron Elite' (+ cymoxanil+ oxadixyl+
thiram) (Syngenta); 'Ashlade Mancarb ' (+ maneb) (Ashlade); 'Bayer
UK 413' (+ tebuconazole) (spray, UK) (Bayer); 'Bolda' (+ maneb+
sulfur) (Atlas Crop Protection); 'Bravocarb' (+ chlorothalonil)
(Syngenta); 'Cartoon' (+ tebuconazole) (spray, France) (Bayer);
'Cukarb' (+ copper oxychloride) (Azot); 'Dual' (+ maneb) (Headland);
'Early Impact' (+ flutriafol) (Cheminova); 'Eria' (+ difenoconazole)
(Syngenta); 'Folicur C' (+ tebuconazole) (spray, South Africa) (Bayer);
'Headland Dual' (+ maneb) (Headland); 'Hortag Tecnacarb' (+ tecnazene)
(Hortag); 'Jonk' (+ diethofencarb) (Philagro); 'Libéro' (+
tebuconazole) (spray, France, Belgium) (Bayer); 'Pacer' (+ flutriafol)
(Cheminova); 'Pacha' (+ iprodione) (Philagro); 'Palette' (+ flutriafol)
(Cheminova); 'Ridomil mbc' (+ metalaxyl) (Syngenta); 'Sumico' (+
diethofencarb) (Syngenta); 'Toreador' (+ tebuconazole) (spray, S.
Africa) (Bayer); 'Trial' (+ difenoconazole) (Syngenta); 'Tripart
Arena Plus' (+ tecnazene) (Tripart); 'Tripart Legion' (+ maneb)
(Tripart); 'Tripart Victor' (+ chlorothalonil+ maneb) (Tripart);
'Vicarben-S' (+ sulfur) (Vipesco); 'Viram Plus' (+ thiram) (Vipesco);
'Zaprawa Funaben T' (+ thiram) (Azot) Discontinued names: 'Delsene'
* (Du Pont); 'Lignasan' * (Du Pont); 'Focal' * (Schering) mixtures:
'Cosmic ' * (+ maneb+ tridemorph) (BASF); 'Punch C' * (+ flusilazole)
(Du Pont); 'Dual' * (+ benoxacor+ metolachlor) (Novartis); 'Hispor
45' * (+ propiconazole) (Novartis); 'MC Flowable' * (+ maneb) (United
Phosphorus); 'New Arena Plus' * (+ tecnazene) (Hickson & Welch);
'Sparkle 45' * (+ propiconazole) (Novartis); 'Stefes Kombat ' *
(+ mancozeb) (Stefes)
Carbendazim ANALYSIS
Product analysis by titration against perchloric acid in acetic
acid or by u.v. spectrophotometry. Residues in crops determined
using methods for benomyl, hplc (J. J. Kirkland et al., J. Agric.
Food Chem., 1973, 21, 368; Pestic. Anal. Man., 1979, II; J. E. Farrow
et al., Analyst (London), 1977, 102, 752) or fluorimetry or colorimetry
of derivatives (H. L. Pease & J. A. Gardiner, J. Agric. Food
Chem., 1969, 17, 267; N. Aharonson & A. Ben-Aziz, J. Assoc.
Off. Anal. Chem., 1973, 56, 1330).
Carbendazim MAMMALIAN TOXICOLOGY
Reviews 74, 76 Oral Acute oral LD50 for rats >15 000, dogs >2500
mg/kg. Skin and eye Acute percutaneous LD50 for rabbits >10 000,
rats >2000 mg/kg. Non-irritating to skin and eyes (rabbits).
Not a skin sensitiser (guinea pigs). Inhalation LC50 (4 h) for rats,
rabbits, guinea pigs or cats, no effect with suspension (10 g/l
water). NOEL (2 y) for dogs 300 mg/kg diet, corresponding to 6-7
mg/kg b.w. ADI (JMPR) 0.03 mg/kg b.w. [1995]. Other Acute i.p. LD50
for male rats 7320, female rats 15 000 mg/kg. Toxicity class WHO
(a.i.) III (Table 5) EC hazard R40
Carbendazim ECOTOXICOLOGY
Birds Acute oral LD50 for quail 5826-15 595 mg/kg. Fish LC50 (96
h) for carp 0.61, rainbow trout 0.83, bluegill sunfish >17.25,
guppy >8 mg/l. Daphnia LC50 (48 h) 0.13-0.22 mg/l. Algae EC50
(72 h) for Scenedesmus subspicatus 419, Selenastrum capricornutum
1.3 mg/l. Bees LD50 (contact) >50 mg/bee. Worms LC50 (4 w) for
Eisenia foetida 6 mg/kg soil.
Carbendazim ENVIRONMENTAL FATE
EHC 149 (WHO, 1993). EHC 149 concludes that, although highly toxic
to aquatic organisms, low bioavailability in surface waters makes
it unlikely this toxicity will occur in the field. Animals In male
rats, following a single oral administration of 3 mg/kg, 66% was
eliminated in the urine within 6 hours. Plants Readily absorbed
by plants. One degradation product is 2-aminobenzimidazole. Soil/Environment
2-Aminobenzimidazole has been found as a minor metabolite. DT50
in soil 8-32 d under outdoor conditions. Carbendazim decomposes
in the environment, DT50 6-12 mo on bare soil, 3-6 mo on turf, and
2-25 mo in water under aerobic and anaerobic conditions, respectively.
It is mainly decomposed by micro-organisms. Koc 200-250.